Adolescent Exposure to Nicotine and Ethanol Attenuates Adult Nicotine Reward Sensitivity in Rats.

Neuropsychopharmacol Rep · 2026 · PMC13240331 · PMID 42157642

Europe PMC DOI

hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

showed a trendp < 0.10so close (0.05 < p ≤ 0.1)

Preliminary Study Only the 0.12 mg/kg nicotine group showed a trend toward increased preference ( t (2) = 3.17, p < 0.10), whereas the 0.04 and 0.08 mg/kg doses produced no significant CPP (Figure 1A ).

also in 53,322 other papers

did not reach statistical significanceno p-value reported

Concurrently, the ethanol preference ratio decreased from approximately 30% on PND 28 to 15% on PND 41, although this change did not reach statistical significance (Figure 1C ). 3.3.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.