The Steroidal Profile Modulates Adaptive Immune Response and Prognosis in Adrenocortical Carcinoma: Analysis of TCR and BCR Repertoires.

Correlations with a p value < 0.05 were considered nominally significant and visualized in heatmaps.

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However, some correlations involving the TRG and TRD chains did not reach statistical significance, likely due to the reduced number of cases with detection of these chains, as previously observed.

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These results demonstrate that, when tumor staging is controlled (at least in Stage II, where comparison was possible), the greater abundance and diversity of BCR and TCR transcripts associated with the LSP phenotype are robust and highly significant characteristics.

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