Effects of the neutral CB1 receptor antagonist AM6527 on spontaneous, consummatory, and motivated behavior in mice.

Psychopharmacology (Berl) · 2026 · PMC13242385 · PMID 41254232

Europe PMC DOI

hedged sentences

0.0865

closest p · 1.7× alpha

0.1240

boldest claim

The sentences

did not reach statistical significancep = 0.0865so close (0.05 < p ≤ 0.1)

In contrast, breakpoint duration did not reach statistical significance (F(3, 48) = 2.33, p = 0.0865, η 2 = 0.127; Fig. 4 D).

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showed a trendp = 0.124not close (p > 0.1)

When analyzed separately, neither group showed statistically significant differences across doses, though the 10.0 mg/kg dose showed a trend toward reduction in both groups ( p = 0.124 in low responders, p = 0.066 in high responders).

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