Barely Significant
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Obinutuzumab alone may be an effective option for adult minimal change disease: a single-center retrospective observational study.

BMC Nephrol · 2026 · PMC13244911 · PMID 42021204

2
hedged sentences
0.0570
closest p · 1.1× alpha
0.1000
boldest claim

The sentences

did not reach statistical significancep = 0.057so close (0.05 < p ≤ 0.1)
While obinutuzumab treatment showed a trend toward a beneficial effect on CR rate after adjustment for covariates, this association did not reach statistical significance ( p = 0.057) (Table 4 ).

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showed a trendp < 0.1so close (0.05 < p ≤ 0.1)
Hypertension and proteinuria showed a trend toward association with CR rate ( p < 0.1) and were therefore included in the multivariate Cox regression model.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.