Ketogenic Diet in Super-Refractory Status Epilepticus: A Retrospective Cohort Study with Severity-Matched Controls in Critically Ill Adults.

Neurocrit Care · 2026 · PMC13249628 · PMID 41507676

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.1280

boldest claim

The sentences

showed a trendp = 0.051so close (0.05 < p ≤ 0.1)

Age showed a trend-level effect (HR 0.96, 95% CI 0.92–1.00, p = 0.051) (Table 2 ).

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a nonsignificant trendp = 0.128not close (p > 0.1)

An exploratory interaction term (KD × ASM burden) showed a nonsignificant trend ( p = 0.128), possibly indicating enhanced KD efficacy in more refractory cases.

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did not reach statistical significanceno p-value reported

Although this unadjusted difference did not reach statistical significance and numerically favored controls, it likely reflects treatment selection and immortal time bias.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.