Barely Significant
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Prognostic Impact and Clinicopathological Significance of TIM-3 and LAG-3 Expressions in Laryngeal Squamous Cell Carcinoma.

Laryngoscope Investig Otolaryngol · 2026 · PMC13253155 · PMID 42292754

2
hedged sentences
0.2650
closest p · 5.3× alpha
0.2650
boldest claim

The sentences

showed a trendp = 0.265not close (p > 0.1)
The TIM‐3 positive group showed a trend toward poorer outcomes in terms of DSS ( p = 0.265), DFS ( p = 0.168), and RFS ( p = 0.059), without statistical significance (Figure 4 ).

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While the LAG‐3 positive group did show a trend toward worse outcomes in terms of DSS ( p = 0.098) and DFS ( p = 0.101), this difference did not reach statistical significance (Figure 5 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.