Anthracycline dose showed a weak negative correlation with post-NACT AMH, but this association did not reach statistical significance (R = −0.18, p = 0.12) ( Figure 3 C).
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Early Ovarian Reserve Depletion During Neoadjuvant Chemotherapy in Female Patients with Bone and Soft Tissue Sarcoma: A Longitudinal Anti-Müllerian Hormone Study.
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0.1200
0.2350
The sentences
nominally significantp = 0.235
Cyclophosphamide dose, which appeared nominally significant in the untransformed analysis ( Supplementary Table S1 ), was not replicated in the log-transformed model (β = −0.001, p = 0.235), suggesting that the original signal reflected the combined influence of AMH non-normality, regimen-structured collinearity, and the small number of cyclophosphamide-treated patients ( n = 12/75) rather than a true independent pharmacological effect.