Barely Significant
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Early Ovarian Reserve Depletion During Neoadjuvant Chemotherapy in Female Patients with Bone and Soft Tissue Sarcoma: A Longitudinal Anti-Müllerian Hormone Study.

Cancers (Basel) · 2026 · PMC13256773 · PMID 42279403

2
hedged sentences
0.1200
closest p · 2.4× alpha
0.2350
boldest claim

The sentences

did not reach statistical significancep = 0.12not close (p > 0.1)
Anthracycline dose showed a weak negative correlation with post-NACT AMH, but this association did not reach statistical significance (R = −0.18, p = 0.12) ( Figure 3 C).

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nominally significantp = 0.235not close (p > 0.1)
Cyclophosphamide dose, which appeared nominally significant in the untransformed analysis ( Supplementary Table S1 ), was not replicated in the log-transformed model (β = −0.001, p = 0.235), suggesting that the original signal reflected the combined influence of AMH non-normality, regimen-structured collinearity, and the small number of cyclophosphamide-treated patients ( n = 12/75) rather than a true independent pharmacological effect.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.