Differential efficacy and anti-inflammatory mechanisms of Bailing Preparations versus Huangkui Capsules combined with SGLT-2 inhibitors for diabetic kidney disease: a network meta-analysis and GRADE assessment.

Front Pharmacol · 2026 · PMC13260605 · PMID 42292842

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did not reach statistical significanceno p-value reported

Although the network comparison between the two drugs did not reach statistical significance, the SUCRA ranking placed Bailing Preparations (81.8%) first, indicating its best potential for protecting glomerular filtration function.

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showed a trendno p-value reported

Our safety analysis revealed that combining SGLT-2i with CCPPs did not exacerbate these risks, but rather showed a trend towards reducing overall adverse events (RR < 1).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.