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HBV status modulates transaminase decrease after switching from tenofovir disoproxil fumarate to tenofovir alafenamide in people with HIV.

J Antimicrob Chemother · 2026 · PMC13266268 · PMID 41665334

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Notably, individuals with possible occult HBV demonstrated a trend towards a further reduction in transaminase levels compared to those without HBV, although this difference did not reach statistical significance.

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showed a trendno p-value reported
Our study showed a trend towards a greater reduction in transaminase levels in the pOBI group compared to HBV-negative individuals, although this difference did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.