Barely Significant
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In vivo functional profiling and structural characterization of the human <i>GLP1R</i> A316T variant.

Sci Adv · 2026 · PMC13267291 · PMID 41637494

Europe PMCDOI
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near-significantno p-value reported
Consequently, we observed a near-significant reduction in prolonged minus acute effects for semaglutide in hGLP1R A316T/A316T compared to hGLP1R +/+ mice (fig.

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did not reach statistical significanceno p-value reported
Parallel experiments in islets from HFHS-fed mice showed similar tendencies which, however, did not reach statistical significance (fig.

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