Phenotypic diversity is caused by non-linear genetic interactions between two SNAREopathy genes.

Mol Psychiatry · 2026 · PMC13268963 · PMID 41781723

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.0670

boldest claim

The sentences

showed a trendp = 0.010actually significant

3G ) and Stxbp1 single mutants showed a trend towards longer escape latencies compared to controls and Snap25 single mutants (p = 0.010 and 0.057, respectively Fig. 3G ).

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a strong trendp = 0.058so close (0.05 < p ≤ 0.1)

Increased c-Fos expression was observed in cortical brain regions of Stxbp1 single mutants as shown before [ 13 ], in the surviving double mutants (p = 0.026) and a strong trend was observed in Snap25 single mutants (p = 0.058) (Fig. 2A, B and E ).

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an overall trendp = 0.067so close (0.05 < p ≤ 0.1)

5A ) but did show an overall trend towards increased frequency of active cells (F(1,90) = 3.463, p = 0.067, Supplementary Fig. 5B and Supplementary Table 1 ).

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