Age-dependent vulnerability to spatial memory interference in APP/PS1 mice.

Front Aging Neurosci · 2026 · PMC13269207 · PMID 42311499

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hedged sentences

0.0610

closest p · 1.2× alpha

0.0690

boldest claim

The sentences

showed a trendp = 0.061so close (0.05 < p ≤ 0.1)

Updated comparison, the linear regression was significant ( p = 0.033) while Spearman correlation showed a trend ( p = 0.061; Figure 2C right).

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did not reach statistical significancep = 0.069so close (0.05 < p ≤ 0.1)

In contrast, although only 44.44% of younger APP/PS1 mice met the criterion, the difference from controls did not reach statistical significance (4–7 months: p = 0.069, control DI ≥ 25: 72.73%, APP/PS1 DI ≥ 25: 44.44%, binomial test, Figure 4D top,).

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