Barely Significant
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The Pathogenic ADAMTSL2 D167N Variant Causes Geleophysic Dysplasia-Like Connective Tissue Changes in Mice.

Am J Pathol · 2026 · PMC13269634 · PMID 41864337

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showed a trendno p-value reported
In the hind limbs, the difference in relative bone shortening between long bones (10.9%) and metatarsals (15.3%) showed a trend but did not reach statistical significance ( P = 0.065) ( Figure 6 , C and D).

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The reduction in body weight did not reach statistical significance because the only male in the D167N group had an increased body weight compared with the two D167N females.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.