Barely Significant
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Investigation of stress hormones across multiday seizure cycles.

Brain Commun · 2026 · PMC13270484 · PMID 42311452

2
hedged sentences
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)
Morning cortisol levels were 37% higher (OR = 1.37, CI: 1.02–1.87) during multiday seizure cycle peaks compared with troughs, although this effect did not reach statistical significance ( P = 0.07).

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a significant trendno p-value reported
There was, however, a significant trend for increased evening cortisol within 12 h of seizures, which may become more pronounced with more accurate seizure capture.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.