Phase-dependent reorganization of circulating miRNA networks following short maximal exercise.

Front Physiol · 2026 · PMC13271730 · PMID 42311326

Europe PMC DOI

hedged sentences

0.0670

closest p · 1.3× alpha

0.2400

boldest claim

The sentences

did not reach statistical significancep = 0.067so close (0.05 < p ≤ 0.1)

Among the investigated miRNAs, miR-122 demonstrated the largest acute response, with a median log 2 fold change of −1.03 (IQR −2.12 to −0.60), corresponding to an approximately twofold decrease and a large effect size (r = 0.56), although the result did not reach statistical significance (p = 0.067). miR-103, miR-144 and miR-486 showed no significant immediate changes following exercise.

also in 111,027 other papers

a negative trendp = 0.24not close (p > 0.1)

Training volume also showed a negative trend with peripheral desaturation (ΔStO 2 ; ρ = −0.39, p = 0.24), whereas no associations were found between training volume and miR-103, miR-122, or cortisol responses.

also in 4,201 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.