In the IPW analysis, (advanced imaging as reference), simple imaging showed numerically worse point estimates across all outcomes, although most differences did not reach statistical significance: a worse mRS shift (adjusted odds ratio [aOR] 1.17 [95% CI, 0.96–1.43]; P = .11), a lower good functional outcome (mRS 0–2; aOR 0.83 [0.66–1.06]; P = .13), a higher mortality (aOR 1.20 [0.91–1.58]; P = .20), more frequent sICH (aOR 1.25 [0.61, 2.57]; P = .55) and a higher risk of any ICH (aOR 1.57 [1.00–2.47]; P = .05).
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Simple against advanced imaging for the selection of stroke therapy in the extended window (VESTA study).
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The sentences
All subgroups showed a trend towards better functional outcomes with advanced imaging; this trend approached statistical significance in patients with proximal occlusion ( Table 3 ).