Circadian and Sleep-Related Polygenic Scores in Relation to Lithium Treatment Response in Bipolar Disorder.

Neuropsychobiology · 2026 · PMC13275051 · PMID 41989970

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did not reach statistical significanceno p-value reported

In contrast, the other sleep-related polygenic scores did not reach statistical significance.

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nominally significantno p-value reported

Regarding the polygenic burden analyses, we found a nominally significant association between the PGS for ease of getting up and Li treatment response.

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