Rim enhancement on MRI predicts long-term outcomes in extruded/migrated lumbar disc herniation managed with an inflammation-preserving protocol: a 6-year prospective cohort study.

Results demonstrated a highly significant main effect of time ( F = 278.003, P < 0.001), indicating that herniation volume significantly decreased at all postoperative time points compared to preoperative levels across all patients.

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Multivariate linear regression analysis, adjusting for age, gender, symptom duration, and baseline herniation volume, revealed that baseline herniation volume was the strongest independent predictor of JOA improvement rate ( B = 0.035, P < 0.001), while rim enhancement showed a trend toward independent predictive value ( B = 0.156, P = 0.092).

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Although the mean duration of illness was numerically longer in the Positive group (51.79 days) than in the Negative group (40.71 days), this difference did not reach statistical significance, and the substantial standard deviations indicate notable heterogeneity within each group.

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