QeITH: Quantifies Tumor Ecosystem Heterogeneity to Predict Cancer Progression and Treatment Benefit.

Comput Struct Biotechnol J · 2026 · PMC13276245 · PMID 42328538

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.1140

boldest claim

The sentences

approaching significanceP = 0.052so close (0.05 < p ≤ 0.1)

In contrast, QeITH detected significant tumor-normal differences in the kidney cancer dataset ( P < 0.05) and showed trends approaching significance in the lung cancer dataset ( P = 0.052 and P = 0.059).

also in 2,640 other papers

did not reach statistical significanceP = 0.114not close (p > 0.1)

In the paired single-cell data, the cell composition-based ITH scores showed a weaker association that did not reach statistical significance ( P = 0.114), although we note the limited sample size of the nonresponder group.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.