Conduction system pacing compared with biventricular pacing for cardiac resynchronization therapy: a systematic review and meta-analysis.

Front Cardiovasc Med · 2026 · PMC13278982 · PMID 42325689

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.2200

boldest claim

The sentences

showed a trendP = 0.06so close (0.05 < p ≤ 0.1)

Among three RCTs (254 patients), CSP showed a trend toward improved NYHA class that did not reach statistical significance (MD: −0.16; 95% CI: −0.34–0.01; P = 0.06; I 2 = 0%).

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did not reach statistical significanceP = 0.22not close (p > 0.1)

Among ten RCTs (723 patients), CSP demonstrated a trend toward greater LVEF improvement that did not reach statistical significance (MD: 1.46%; 95% CI: −0.87%–3.80%; P = 0.22; I 2 = 55%).

also in 77,393 other papers

a favorable trendno p-value reported

With respect to ACM, LBBAP was associated with reduced mortality (RR: 0.74), mixed CSP showed a favorable trend (RR: 0.80), and LVSP was associated with significantly increased mortality (RR: 4.00).

also in 1,053 other papers

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