Elevated Interleukin-6 Levels in Socioeconomically Disadvantaged Children With Borderline Subclinical Rheumatic Heart Disease in São Paulo, Brazil: A Prospective Cohort Study Highlighting Early Detection and Treatment Opportunities.

J Am Heart Assoc · 2026 · PMC13279056 · PMID 41944184

Europe PMC DOI

hedged sentences

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

showed a trendP =0.067so close (0.05 < p ≤ 0.1)

At baseline, IL‐6 levels were significantly higher in the borderline SCRHD group compared with controls ( P =0.048), while tumor necrosis factor‐alpha showed a trend toward elevation ( P =0.067).

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did not reach statistical significanceno p-value reported

Although TNF‐α levels did not reach statistical significance, a trend toward elevation was observed in the borderline SCRHD.

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