qPCR confirmed a significant induction of Cdkn1a and C4b in CTK-treated cells, while Serpina3 showed an increasing trend that did not reach statistical significance ( Figures 5C–E ).
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The GPR17 agonist galinex restores oligodendrocyte maturation under inflammatory conditions.
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Relative to control cells, exposure to CTK-2 showed a trend toward reduced complexity in the peak/early-decay region but did not reach significance in this dataset when tested per radius ( Figures 6E,F ).