Efficacy of hyaluronic acid and butyroyl glutathione in the management of glaucoma-related ocular surface disease: a prospective, interventional, double-blind, cross-over post market study.

Front Pharmacol · 2026 · PMC13279420 · PMID 42328630

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0560

boldest claim

The sentences

highly significantp < 0.001actually significant

Statistically significant comparisons were considered at p < 0.05, with exact p-values reported; for highly significant findings, p < 0.001 is indicated.

also in 82,756 other papers

borderline significantp = 0.054so close (0.05 < p ≤ 0.1)

The change in group-level Schirmer values reached a borderline significant p-value (p = 0.054), however, considering the small sample size, the significant correlation with multiple cytokines at the V3 time point supports the efficacy of the combined treatment with GSH-C4.

also in 6,822 other papers

showed a trendp = 0.056so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

In the second half of the study period (i.e., from V4 to V6), Sequence 1 (i.e., HA-first) showed a trend toward lower OSDI scores (p = 0.056) that did not reach statistical significance.

also in 33,481 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.