Clinical severity-dependent virulence of <i>Staphylococcus aureus</i> from human diabetic foot ulcers drives impaired wound healing in a diabetic murine model.

Although a clear trend toward improved healing in Grade 2-infected wounds compared to Grade 4-infected wounds, the difference in histology scores between the Grade 4-infected wounds (histology score: 2.33 ± 0.58) and Grade 2-infected wounds (histology score: 4.25 ± 1.26) at day 14 did not reach statistical significance ( Figure 6M , p = 0.0857).

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