Early-life rotavirus infection susceptibility and later gastrointestinal cancer protection: Reverse antagonistic pleiotropy and potential vaccine benefits.

Curr Res Microb Sci · 2026 · PMC13280574 · PMID 42325863

Europe PMC DOI

hedged sentences

0.0002

closest p · 0.0× alpha

0.0550

boldest claim

The sentences

borderline significance-Log 10 P -value=3.71actually significant

near-significant-Log 10 P -value=1.04so close (0.05 < p ≤ 0.1)

In contrast, rs4304220 on chromosome 7 (6,243 SNPs) showed borderline significance: it was significant for RSB ( RSB =3.55, -Log 10 P -value=3.71) and near-significant for XP-EHH ( XP-EHH =1.33, -Log 10 P -value=1.04), also with positive values pointing to recent positive selection in the HC group ( Fig. 3 B).

also in 7,017 other papers

did not reach statistical significanceP -value=0.055so close (0.05 < p ≤ 0.1)

While the P -value for PRKCH in this dataset did not reach statistical significance, it was close to the threshold ( P -value=0.055); Fig. 4 B.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.