Paraben and Phthalate Exposure in Adolescents With Attention-Deficit/Hyperactivity Disorder: A Case-Control Study.

Attention to phthalate content was reported only in the patient group and showed a trend-level group difference ( Table 6 ).

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Consistent with our results, a study conducted among Dutch adolescents aged 13– 15 years reported a trend toward significance, indicating that higher urinary propyl paraben concentrations were associated with poorer attention performance [ 8 ].

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In particular, the observation of significant or near-significant increases in diethyl phthalate and several other phthalate metabolites among adolescents who used cosmetic products; the associations of deodorant/perfume use with diisopentyl phthalate, face/body cream use with benzyl butyl phthalate, and face/body wash use with di-n-hexyl phthalate support the possibility that these compounds may enter the body through product formulations or packaging materials.

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