Punishment of ethanol choice in group-housed male cynomolgus monkeys.

Despite the lack of a rank-related difference in these measures, there was a strong positive relationship found between quinine EC 50 values and the volume of ethanol consumed at baseline that approached significance (r 2 =0.70, p = 0.08; Fig. 5 ) as well as a significant positive relationship between quinine EC 50 and baseline ethanol intake (r 2 = 0.80, p = 0.04; Fig. 5 ), but only in dominant monkeys.

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Ethanol choice At the outset of these experiments, although subordinate monkeys had considerably higher lifetime average ethanol intakes, the difference between dominant and subordinate monkeys did not reach statistical significance (t(8) = 1.81, p = 0.11).

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When all monkeys were combined, however (n = 10), there was a trend toward significance in the relationship between EC 50 values and ethanol choice (r 2 = 0.29, p = 0.11).

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