At a low effector-to-target ratio (2:1), cutaneous γδ T cells exhibited increased tumor cell killing compared with αβ T cells, although this difference did not reach statistical significance (fig.
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Harnessing skin-resident γδ T cells for immunotherapy in cutaneous squamous cell carcinoma.
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The sentences
In line with the observed increased expression cytotoxicity markers, γδ T cells demonstrated in vitro cytotoxic activity against SCC cells and showed a trend toward enhanced killing compared with cutaneous αβ T cells at low effector-to-target ratios, consistent with their rapid, innate tumor recognition capacity ( 1 ).