Multidrug-Resistance Patterns and Predictors in Adult Acute Pyelonephritis: A Three-Year Cohort from a Tertiary Romanian Center with Derivation of the PYELO-MDR-Risk Score

Biomedicines · 2026 · PMC13297201

Europe PMC

hedged sentences

0.0750

closest p · 1.5× alpha

0.1930

boldest claim

The sentences

borderline significancep = 0.075so close (0.05 < p ≤ 0.1)

12.0%), although the difference reached only borderline significance ( p = 0.075), likely reflecting power constraints inherent to the cohort size.

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did not reach statistical significancep = 0.193not close (p > 0.1)

Nephrolithiasis/urolithiasis was also more frequent among MDR cases but did not reach statistical significance (20.4% vs. 12.0%; p = 0.193).

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approached significanceno p-value reported

After multivariable adjustment, four exposures retained independent associations with MDR pyelonephritis at the conventional 0.05 threshold, and an additional three covariates approached significance.

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