A Hypoxia-Apoptosis Stress-Adaptation State Defines Immune-Low Melanoma and Predicts Metastatic Risk

Cancers (Basel) · 2026 · PMC13297633

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closest p

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did not reach statistical significancep = 0.076so close (0.05 < p ≤ 0.1)

an unfavorable trendno p-value reported

For progression-free interval, the high-BiScore group also showed an unfavorable trend, although the difference did not reach statistical significance ( Figure 4 D, log-rank p = 0.076).

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