Barely Significant
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Prognostic Value of the Gustave Roussy Immune Score in Patients with Locally Advanced Gastric Cancer Receiving Neoadjuvant FLOT Chemotherapy: A Retrospective Cohort Study

Diagnostics (Basel) · 2026 · PMC13298714

2
hedged sentences
0.0980
closest p · 2.0× alpha
0.1830
boldest claim

The sentences

showed a trendp = 0.098so close (0.05 < p ≤ 0.1)
Histological subtype showed a trend toward worse PFS for signet-ring-cell carcinoma than for adenocarcinoma (HR: 1.517, 95% CI: 0.926–2.485, p = 0.098).

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did not reach statistical significancep = 0.183not close (p > 0.1)
In exploratory analyses using the cohort-specific NLR cutoff value (3.43), patients with NLR < 3.43 demonstrated a numerically longer median overall survival (50.3 months) than those with NLR ≥ 3.43 (39.5 months); however, this difference did not reach statistical significance (log-rank p = 0.183).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.