Tripterygium wilfordii Hook F accelerates CD4<sup>+</sup> T-cell recovery in ART-treated people living with HIV with incomplete immune reconstitution: a longitudinal cohort study.

By contrast, CD8 + T-cell counts did not differ significantly between groups during the treatment period at the cross-sectional level (TwHF-M6 through Post-M12, all P > 0.05; Supplementary Table S1 ), although linear mixed-effects modeling showed a nominally significant group × time interaction for CD8 + T-cell counts ( P = 0.041; Supplementary Table S2 ), suggesting a differential longitudinal trajectory that warrants further investigation.

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Eotaxin levels showed a positive numerical trend (median Δ +13.11 pg/mL) that did not reach statistical significance ( P = 0.216; Figure 3A ).

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