Barely Significant
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MicroRNA Dysregulation and Hepatic Involvement in Alcohol-Related Macrocytic Anaemia: Links to Severity Without Predictive Value for Treatment Response

Life (Basel) · 2026 · PMC13301919

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ALT and AST did not reach statistical significance, suggesting subclinical or predominantly cholestatic hepatic involvement rather than overt hepatocellular damage in this sample.

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nominally significantno p-value reported
Associations that remained significant after adjustment were considered more robust, whereas nominally significant unadjusted associations were interpreted as exploratory.

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highly significantno p-value reported
As with the other miRNAs, inverse correlations with hemoglobin (rho = −0.575, p < 0.001) and hematocrit (rho = −0.575, p < 0.001) and a positive correlation with MCV (rho = 0.524, p < 0.001) were highly significant, confirming a consistent pattern of erythroid disruption across all three markers.

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