Donor-specific pathological features associate with genetic background, lesion type distribution, and clinical heterogeneity in multiple sclerosis.

Acta Neuropathol · 2026 · PMC13303759 · PMID 42350827

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0570

boldest claim

The sentences

showed a trendP = 0.050actually significant

Donors with perivascular cuffs showed a trend ( P = 0.050) toward enrichment of this genotype.

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did not reach statistical significanceP = 0.057so close (0.05 < p ≤ 0.1)

Lastly, donors lacking all four pathological features tended to die at an older age, although this did not reach statistical significance ( P = 0.057).

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