Casein hydrolysate promotes intestinal repair in adult mice with <i>Salmonella enteritis</i> through a lactate-GPR81-Wnt3A axis in intestinal stem cell niche.

Colonic length was significantly shortened in adult mice of the model group (p < 0.0001), whereas colonic length in the model + CEH group showed a trend toward recovery, although the difference did not reach statistical significance ( Figures 1F, G ). 3.2 Casein hydrolysate preserves intestinal mucosal architecture and goblet cell integrity At the histological level, PAS staining of the ileum showed that the number of goblet cells in the crypt region was markedly lower in the model group than in the control group, indicating damage to the mucus-secreting barrier ( Figure 2A ).

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