Short- and Long-Term Effectiveness and Safety of Vedolizumab in Crohn's Disease: A Multicenter Retrospective Study from the Hokkaido Phoenix Cohort.

Inflamm Intest Dis · 2026 · PMC13313623 · PMID 42376456

Europe PMC DOI

hedged sentences

0.0610

closest p · 1.2× alpha

0.0850

boldest claim

The sentences

did not reach statistical significancep = 0.061so close (0.05 < p ≤ 0.1)

Patients without intestinal structural complications tended to have higher continuation rates than those with strictures or fistulas, although this difference did not reach statistical significance ( p = 0.061, Fig. 2 c).

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showed a trendp = 0.085so close (0.05 < p ≤ 0.1)

Similarly, patients with an ileal disease phenotype showed a trend toward better treatment persistence compared with those with non-ileal disease ( p = 0.085, Fig. 2 d).

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