Association of the TyG index and its body fat distribution composites with CHD and MACE risk in adults with OSAHS: incremental discrimination and exploratory mediation analysis.

Front Endocrinol (Lausanne) · 2026 · PMC13314442 · PMID 42381877

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hedged sentences

0.1590

closest p · 3.2× alpha

0.1590

boldest claim

The sentences

did not reach statistical significanceP = 0.159not close (p > 0.1)

Conversely, TyG-BRI did not reach statistical significance in Model 3 (HR = 1.185, 95% CI 0.936–1.499, P = 0.159).

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failed to reach statistical significanceno p-value reported

Multiple sensitivity analyses, including additional adjustment for ALT, replacement of LDL-C with TC, and substitution of AHI with mean oxygen saturation or lowest oxygen saturation, yielded directionally consistent findings overall: the indirect pathway signal for TyG-WWI was the most stable, followed by TyG-CVAI, whereas the indirect effects of TyG and TyG-BRI were generally weaker and mostly failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.