Multiomics immune profiling of a patient-relevant orthotopic lung cancer model using SEPARATE-Seq.

Nat Commun · 2026 · PMC13315217 · PMID 42026061

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

a clear trendp = 0.08so close (0.05 < p ≤ 0.1)

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

While the combination therapy did not reach statistical significance over chemotherapy alone, a clear trend toward improved response was observed (Cis vs Combo, p = 0.08), mirroring clinical observations in advanced NSCLC patients 85 , 86 .

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