Milk-derived extracellular vesicles loaded with miR-146a-5p as a novel therapeutic strategy for allergic airway inflammation.

Mol Ther Nucleic Acids · 2026 · PMC13316569 · PMID 42381703

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a mild trendno p-value reported

did not reach statistical significanceno p-value reported

Notably, while this group exhibited a mild trend toward reduced inflammation, the effect did not reach statistical significance.

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showed a trendno p-value reported

The NC-miRNA-mEVs, which were loaded with nonsense miRNA sequences, showed a trend of reducing type 2 inflammatory cytokine levels, but there was no statistically significant difference compared with the inflammation stimulation group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.