Selective lymphodepletion underlies the efficacy of horse anti-thymocyte globulin-based immunosuppressive therapy in aplastic anemia.

Although these associations did not reach statistical significance, the observed trend could be suggestive of a possible relationship between active ATGAM exposure and the timing of hematologic recovery.

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Within two weeks post-ATGAM, both memory T cells and CD27 + B-cell frequencies showed a trend towards normalization (Figure 5A-C).

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