Clinical and autonomic correlates of chronic Sialorrhea in Parkinson's disease: a questionnaire-based study with cluster analysis of autonomic and dysphagia burden.

Clin Park Relat Disord · 2026 · PMC13320329 · PMID 42389237

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

showed a trendp = 0.056so close (0.05 < p ≤ 0.1)

MIBG myocardial scintigraphy indices showed a trend toward higher early H/M ratios in cluster B ( p = 0.056, Cohen's d = 0.68), whereas delayed H/M ratios and washout rates did not differ significantly across clusters. 4 Discussion In this questionnaire-based study of Japanese outpatients with PD, chronic sialorrhea was common and was associated with male sex, longer disease and treatment duration, greater motor severity, and a substantially higher burden of autonomic symptoms.

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did not reach statistical significanceno p-value reported

Drooling severity also varied across clusters: DSFS scores were higher in cluster B than in cluster A ( p = 0.014) and tended to be higher in cluster C than in cluster A, although this difference did not reach statistical significance after correction.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.