Impact of tirzepatide on systemic arterial stiffness assessed by cardio-ankle vascular index in individuals with obesity complicated by type 2 diabetes: A retrospective cohort study in Japan.

Obes Pillars · 2026 · PMC13320546 · PMID 42388688

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0890

boldest claim

The sentences

showed a trendp = 0.057so close (0.05 < p ≤ 0.1)

The urinary albumin/creatinine ratio (UACR) tended to decrease with tirzepatide (median 11.9 to 7.2 mg/gCr, p = 0.067), and change in (Δ)UACR showed a trend of positive correlation with ΔCAVI ( r s = 0.403, p = 0.057).

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did not reach statistical significancep = 0.089so close (0.05 < p ≤ 0.1)

2 A, CAVI reduction tended to be greater in the high-dose group compared to the low-dose group, although the difference did not reach statistical significance ( p = 0.089).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.