Genome-wide variation in cell-free DNA end-motif entropy predicts immunotherapy response in head and neck cancer.

J Clin Invest · 2026 · PMC13322381 · PMID 42154530

Europe PMC DOI

hedged sentence

0.1970

closest p · 3.9× alpha

0.1970

boldest claim

The sentences

showed a trendP = 0.197not close (p > 0.1)

did not reach statistical significanceno p-value reported

For OS, although rMDS-predicted responders showed a trend toward improved outcomes (log-rank test, P = 0.197), this did not reach statistical significance.

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