Efficacy, tolerability and barriers to the use of anti-CGRP medications among migraine patients in Egypt: real world experience.

3.6 Clinical characteristics and patterns of treatment response Exploratory analyses of treatment response in relation to patient characteristics—including demographic factors (age, sex, comorbidities, age at onset), headache features (location, character, and associated symptoms), and baseline headache diary parameters (monthly migraine days, attack duration, intensity, analgesic use, and crystal-clear days)—suggested that the presence of medication overuse headache was associated with a lower likelihood of response, although this did not reach statistical significance.

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Exploratory analyses suggested that treatment adherence and insurance coverage were associated with more favorable response patterns, while medication overuse headache showed a trend toward reduced response, although not statistically significant.

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