Long-term neuromuscular alterations during botulinum toxin treatment for chronic migraine.

Group 4 showed a trend toward higher mean jitter values (mean 51 ± 29 μs; range 28–110 μs), but between-group differences were not significant ( Fig. 5 ).

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No significant differences in MUP amplitudes or durations were found between injected and non-injected patients at week 1, and although a trend toward lower amplitudes was observed at week 12 among BoNTA-treated individuals, this did not reach statistical significance. 4.1.1 Myopathic pattern more common in long-term BoNTA treatment A myopathic EMG pattern was substantially more common among patients with long-term exposure to BoNTA.

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