Once-Weekly Somatrogon in Pediatric Growth Hormone Deficiency: Real-World Efficacy, Safety, and Quality-of-Life Findings

Although body composition changes did not reach statistical significance, these data provide preliminary insight into the broader effects of somatrogon treatment and should be interpreted cautiously and confirmed in larger studies with longer follow-up.

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The near-significant trend in PedsQL Psychosocial domain scores among naïve patients may be indicative of a patient-perceived benefit that warrants testing in larger, longer studies with 12-month QoL endpoints.

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