Therapeutic Apheresis for Intravenous Methylprednisolone-Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single-Center Case Series.

Ther Apher Dial · 2026 · PMC13326961 · PMID 41956089

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

showed a trendp = 0.09so close (0.05 < p ≤ 0.1)

In this subgroup analysis of IVIg‐naïve patients, the difference in lesion area showed a trend (5.0 ± 4.0 vs. 1.1 ± 0.27 cm 2 , p = 0.09).

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failed to reach statistical significanceno p-value reported

This result may reflect a true effect that failed to reach statistical significance owing to the limited sample size and insufficient statistical power.

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