Trends, survival and regional control of sentinel lymph node biopsy versus axillary dissection in cN0 breast cancer: a multicenter cohort in China.

Front Oncol · 2026 · PMC13341454 · PMID 42421681

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a clear trendno p-value reported

Although our temporal analysis confirms a clear trend toward axillary de-escalation, with ALND rates in pN0 patients declining to 24.7% by 2022, this persistence of dissection highlights a divergence from international consensus ( 23 , 24 ).

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did not reach statistical significanceno p-value reported

In patients who did not receive chemotherapy, the absolute 5-year difference in cumulative RNR was 6.19%; however, the adjusted association did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.