Enhanced Discrimination of Coronary Artery Disease Severity by Circulating Phoenixin-14: Evidence from a Clinical Laboratory Study.

Int J Mol Sci · 2026 · PMC13361344 · PMID 42449992

Europe PMC DOI

hedged sentences

0.0750

closest p · 1.5× alpha

0.0750

boldest claim

The sentences

did not reach statistical significancep = 0.075so close (0.05 < p ≤ 0.1)

However, these differences did not reach statistical significance ( p = 0.075), indicating limited discriminatory performance in the present cohort ( Figure 1 C).

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a decreasing trendno p-value reported

Alamandine levels showed a decreasing trend across groups, with the lowest concentrations observed in patients with severe CAD [62.5 (44.4–87.0) pg/mL], followed by non-critical CAD [70.4 (55.6–110.6) pg/mL], and the highest values in the controls [81.3 (53.9–121.1) pg/mL].

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nominally significantno p-value reported

The remaining nominally significant associations—Phoenixin-14 with body mass index ( r = 0.382) and weight ( r = 0.361), Alamandine with glucose ( r = 0.308), and Cerebellin-1 with triglycerides ( r = 0.262)—did not retain significance after correction for multiple comparisons ( Table 3 ).

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