Anle138b ameliorates pathological phenotypes in mouse and cellular models of Huntington's disease.

EMBO Mol Med · 2026 · PMC13365221 · PMID 42362792

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showed a trendno p-value reported

Iba1 levels in placebo-treated mice showed a trend towards an increase, which did not reach statistical significance.

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did not reach statistical significanceno p-value reported

We also observed a trend towards increased Iba1 immunoreactive area in placebo-treated R6/2 mice, but this effect did not reach statistical significance, precluding us from assessing the impact of anle138b on microglia (Fig.

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